abstract：BACKGROUND:Major investments have been made since 2001, with intensification of malaria control interventions after 2006. Interventions included free distribution of insecticide-treated nets (ITN) to pregnant women and children under 5 years old, the introduction of artemisinin combination therapy (ACT) for malaria tre...

journal_title：Malaria journal

authors： Kayentao K,Florey LS,Mihigo J,Doumbia A,Diallo A,Koné D,Doumbo O,Eckert E

更新日期：2018-11-14 00:00:00

abstract：BACKGROUND:Deltamethrin-impregnated, long-lasting insecticidal nets (LLINs) were distributed in the study area from November 2014 to January 2015 to evaluate their impact on malaria transmission in the presence of insecticide-resistant vectors. Studies were carried out in 16 selected clusters in Keshkal sub-district, C...

journal_title：Malaria journal

authors： Kona MP,Kamaraju R,Donnelly MJ,Bhatt RM,Nanda N,Chourasia MK,Swain DK,Suman S,Uragayala S,Kleinschmidt I,Pandey V

更新日期：2018-11-08 00:00:00

abstract：BACKGROUND:Resistance of Plasmodium falciparum to anti-malarial drugs has hampered efforts to eradicate malaria. Recent reports of a decline in the prevalence of chloroquine-resistant P. falciparum in several countries, including Malawi and Zambia, is raising the hope of reintroducing chloroquine in the near future, id...

journal_title：Malaria journal

authors： Dagnogo O,Ako AB,Ouattara L,Dago ND,Coulibaly DN,Touré AO,Djaman JA

更新日期：2018-11-07 00:00:00

abstract：BACKGROUND:Malaria control largely depends on availability of highly efficacious drugs, however, over the years, has been threatened by emergence of drug resistance. It is, therefore, important to monitor the impact of recurrent anti-malarial treatment on the long-term efficacy of anti-malarial regimens, especially in ...

journal_title：Malaria journal

authors： Byakika-Kibwika P,Nyakato P,Lamorde M,Kiragga AN

更新日期：2018-10-30 00:00:00

abstract：BACKGROUND:Post-malaria neurological syndrome (PMNS) is a debated entity, defined by neurological complications following a post-malaria symptom-free period and a negative blood smear. Four cases of PMNS are hereby reported and a review the literature performed to clarify the nosological framework of this syndrome. ME...

journal_title：Malaria journal

authors： Tamzali Y,Demeret S,Haddad E,Guillot H,Caumes E,Jauréguiberry S

更新日期：2018-10-26 00:00:00

abstract：BACKGROUND:Determination of the genetic diversity of malaria parasites can inform the intensity of transmission and identify potential deficiencies in malaria control programmes. This study was conducted to characterize the genetic diversity and allele frequencies of Plasmodium falciparum in Northwest Ethiopia along th...

journal_title：Malaria journal

authors： Mohammed H,Kassa M,Mekete K,Assefa A,Taye G,Commons RJ

更新日期：2018-10-25 00:00:00

abstract：:This opinion article deals with the diagnostic clinical challenges faced by clinicians or health care workers in malaria-endemic areas when a severely sick child presents to the clinic with fever, coma or respiratory distress. Indeed, the coexistence of malaria with other severe infections like meningitis, invasive ba...

journal_title：Malaria journal

authors： Ackerman H,Casals-Pascual C

更新日期：2018-10-22 00:00:00

abstract：BACKGROUND:This study aimed to identify factors at individual and community level influencing insecticide-treated net (ITN) usage among groups of women of childbearing age (WOCBA) in Malawi. METHODS:Factors influencing ITN usage in Malawi were assessed through interviews with 16,130 WOCBA (15-49 years) across 850 comm...

journal_title：Malaria journal

authors： Nkoka O,Chuang TW,Chuang KY,Chen YH

更新日期：2018-10-19 00:00:00

abstract：BACKGROUND:Plasmodium falciparum circumsporozoite protein (PfCSP) is one of the most extensively studied malaria vaccine candidates, but the genetic polymorphism of PfCSP within and among the global P. falciparum population raises concerns regarding the efficacy of a PfCSP-based vaccine efficacy. In this study, genetic...

journal_title：Malaria journal

authors： Lê HG,Kang JM,Moe M,Jun H,Thái TL,Lee J,Myint MK,Lin K,Sohn WM,Shin HJ,Kim TS,Na BK

更新日期：2018-10-12 00:00:00

abstract：BACKGROUND:Malaria can be transmitted by blood transfusion through donations collected from asymptomatic or parasitic donors. The parasites are released into the bloodstream during its life cycle and will therefore be present in donated blood by infected individuals. All cases of transfusion-transmitted malaria (TTM) n...

journal_title：Malaria journal

authors： Batista-Dos-Santos SA,Freitas DRC,Raiol M,Cabral GF,Feio AC,Póvoa MM,Cunha MG,Ribeiro-Dos-Santos Â

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Zoonotic infections with epidemic potential, as non-human primate malaria and yellow fever (YF), can overlap geographically. Optimizing a small blood sample for diagnosis and surveillance is of great importance. Blood are routinely collected for YF diagnosis and blood clots usually discarded after serum obte...

journal_title：Malaria journal

authors： de Abreu FVS,Gomes LR,Mello ARL,Bianco-Júnior C,de Pina-Costa A,Dos Santos E,Teixeira DS,Brasil P,Daniel-Ribeiro CT,Lourenço-de-Oliveira R,de Fátima Ferreira-da-Cruz M

更新日期：2018-09-24 00:00:00

abstract：BACKGROUND:Malaria is a major health problem in sub-Saharan Africa where over 90% of the world's malaria cases occur. Artemisinin-based combination therapy (ACT) is recommended by the World Health Organization as first-line and second-line treatments for uncomplicated falciparum malaria. However, there are a growing nu...

journal_title：Malaria journal

authors： Ndwigah S,Stergachis A,Abuga K,Mugo H,Kibwage I

更新日期：2018-09-15 00:00:00

abstract：:Following publication of the original article [1], one of the authors has highlighted an xml-related discrepancy concerning the author group titled 'Additional Tracking Resistance to Artemisinin Collaboration authors (TRAC Group Authorship)', listed under the Acknowledgements section. ...

journal_title：Malaria journal

authors： Srimuang K,Miotto O,Lim P,Fairhurst RM,Kwiatkowski DP,Woodrow CJ,Imwong M,Tracking Resistance to Artemisinin Collaboration.

更新日期：2018-09-10 00:00:00

abstract：BACKGROUND:The number of clinical cases of malaria is often recorded in resource constrained or conflict settings as a proxy for disease burden. Interpreting case count data in areas of humanitarian need is challenging due to uncertainties in population size caused by security concerns, resource constraints and populat...

journal_title：Malaria journal

authors： Hellewell J,Walker P,Ghani A,Rao B,Churcher TS

更新日期：2018-08-29 00:00:00

abstract：BACKGROUND:As South Africa strives to achieve malaria elimination by 2018 (zero local cases) the country needs to strengthen its disease surveillance system by reducing the timeliness from case diagnosis to notification of key stakeholders in the malaria programme. This study evaluated the feasibility of a 24-h mobile ...

journal_title：Malaria journal

authors： Baloyi RE,Shandukani MB,Graffy R,Misiani E,Mayet N,Mabunda E,Mabuza A,Qwabe B,Ngwenyama B,Reddy C,Moonasar D

更新日期：2018-08-23 00:00:00

abstract：:Unfortunately after publication of the original article [1], it came to the author's attention that there is an error in the caption of Fig. 2. ...

journal_title：Malaria journal

authors： Mwandagalirwa MK,Levitz L,Thwai KL,Parr JB,Goel V,Janko M,Tshefu A,Emch M,Meshnick SR,Carrel M

更新日期：2018-08-08 00:00:00

abstract：:The goal to eliminate malaria from the Asia-Pacific by 2030 will require the safe and widespread delivery of effective radical cure of malaria. In October 2017, the Asia Pacific Malaria Elimination Network Vivax Working Group met to discuss the impediments to primaquine (PQ) radical cure, how these can be overcome and...

journal_title：Malaria journal

authors： Thriemer K,Bobogare A,Ley B,Gudo CS,Alam MS,Anstey NM,Ashley E,Baird JK,Gryseels C,Jambert E,Lacerda M,Laihad F,Marfurt J,Pasaribu AP,Poespoprodjo JR,Sutanto I,Taylor WR,van den Boogaard C,Battle KE,Dysoley L,Ghim

更新日期：2018-06-20 00:00:00

abstract：BACKGROUND:Five species of Plasmodium are known to infect humans. For proper treatment of malaria, accurate identification of the parasite species is crucial. The current gold standard for malaria diagnosis is microscopic examination of Giemsa-stained blood smears. Since the parasite species are identified by microscop...

journal_title：Malaria journal

authors： Hashimoto M,Sakamoto H,Ido Y,Tanaka M,Yatsushiro S,Kajimoto K,Kataoka M

更新日期：2018-06-19 00:00:00

abstract：BACKGROUND:The role of the liver for survival of blood-stage malaria is only poorly understood. In experimental blood-stage malaria with Plasmodium chabaudi, protective vaccination induces healing and, thus, survival of otherwise lethal infections. This model is appropriate to study the role of the liver in vaccination...

journal_title：Malaria journal

authors： Al-Quraishy S,Dkhil MA,Al-Shaebi EM,Abdel-Baki AS,Araúzo-Bravo MJ,Delic D,Wunderlich F

更新日期：2018-05-29 00:00:00

abstract：BACKGROUND:Malaria the first causes of death from parasitic infection worldwide. Interventions to reduce the burden of malaria have produced a tremendous drop in malaria morbidity and mortality. However, progress is slower in DRC, which shares with Nigeria 39% of deaths related to malaria globally. Inappropriate use of...

journal_title：Malaria journal

authors： Ntamabyaliro NY,Burri C,Nzolo DB,Engo AB,Lula YN,Mampunza SM,Nsibu CN,Mesia GK,Kayembe JN,Likwela JL,Kintaudi LM,Tona GL

更新日期：2018-05-03 00:00:00

abstract：BACKGROUND:In Vietnam, malaria transmission has been reduced to very low levels over the past 20 years, and as a consequence, the country aims to eliminate malaria by 2030. This study aimed to characterize the dynamics and extent of the parasite reservoir in Central Vietnam, in order to further target elimination strat...

journal_title：Malaria journal

authors： Kattenberg JH,Erhart A,Truong MH,Rovira-Vallbona E,Vu KAD,Nguyen THN,Nguyen VH,Nguyen VV,Bannister-Tyrrell M,Theisen M,Bennet A,Lover AA,Tran TD,Nguyen XX,Rosanas-Urgell A

更新日期：2018-04-27 00:00:00

abstract：BACKGROUND:Antibody immunity is thought to be essential to prevent severe Plasmodium falciparum infection, but the exact correlates of protection are unknown. Over time, children in endemic areas acquire non-sterile immunity to malaria that correlates with development of antibodies to merozoite invasion proteins and pa...

journal_title：Malaria journal

authors： Kessler A,Campo JJ,Harawa V,Mandala WL,Rogerson SJ,Mowrey WB,Seydel KB,Kim K

更新日期：2018-04-25 00:00:00

abstract：BACKGROUND:Given the risk of artemisinin resistance spreading from the Greater Mekong sub-region, prospective monitoring in sub-Saharan Africa should be expedited. Molecular biology techniques used for monitoring rely on the detection of k13 validated mutants by using PCR and Sanger sequencing approach, usually not ava...

journal_title：Malaria journal

authors： Vachot-Ganée L,Khim N,Iannello A,Legrand E,Kim S,Eam R,Khean C,Ken M,Ashley E,Tun KM,Dhorda M,Nosten F,Souleymane IM,Blein S,Pachot A,Ariey F,Kaiser K,Ménard D

更新日期：2018-04-24 00:00:00

abstract：BACKGROUND:Congenital malaria is the direct infection of an infant with malaria parasites from their mother prior to or during birth. Neonatal malaria is due to an infective mosquito bite after birth. Neonatal and congenital malaria (NCM) are potentially life-threatening conditions that are believed to occur at relativ...

journal_title：Malaria journal

authors： Olupot-Olupot P,Eregu EIE,Naizuli K,Ikiror J,Acom L,Burgoine K

更新日期：2018-04-20 00:00:00

abstract：BACKGROUND:The erythrocytic stage, where malaria parasites proliferate in human blood, is clinically significant as this causes the symptoms and illness of malaria. Experimental rodent models of malaria at the erythrocytic stage are used for the development of anti-malarial drugs and for biological analysis. An automat...

journal_title：Malaria journal

authors： Tougan T,Suzuki Y,Izuka M,Aono K,Okazaki T,Toya Y,Uchihashi K,Horii T

更新日期：2018-04-16 00:00:00

abstract：BACKGROUND:Nicotinamide adenine dinucleotide (NAD+) is an essential molecule in the energy metabolism of living beings, and it has various cellular functions. The main enzyme in the biosynthesis of this nucleotide is nicotinamide/nicotinate mononucleotide adenylyltransferase (NMNAT, EC 2.7.7.1/18) because it is the con...

journal_title：Malaria journal

authors： Nieto CA,Sánchez LM,Sánchez DM,Díaz GJ,Ramírez MH

更新日期：2018-04-11 00:00:00

abstract：BACKGROUND:In the context of malaria elimination/eradication, drugs that are effective against the different developmental stages of the parasite are highly desirable. The oldest synthetic anti-malarial drug, the thiazine dye methylene blue (MB), is known for its activity against Plasmodium blood stages, including game...

journal_title：Malaria journal

authors： Bosson-Vanga H,Franetich JF,Soulard V,Sossau D,Tefit M,Kane B,Vaillant JC,Borrmann S,Müller O,Dereuddre-Bosquet N,Le Grand R,Silvie O,Mazier D

更新日期：2018-04-03 00:00:00

abstract：BACKGROUND:The emergence and spread of Plasmodium falciparum resistance to artemisinin-based combination therapy in Southeast Asia prompted the need to develop new endoperoxide-type drugs. METHODS:A chemically diverse library of endoperoxides was designed and synthesized. The compounds were screened for in vitro and i...

journal_title：Malaria journal

authors： Lobo L,Cabral LIL,Sena MI,Guerreiro B,Rodrigues AS,de Andrade-Neto VF,Cristiano MLS,Nogueira F

更新日期：2018-04-03 00:00:00

abstract：BACKGROUND:Malaria is a major public health problem in endemic countries including Sudan, where about 75% of populations are at risk. Due to widespread of chloroquine-resistant strains of Plasmodium falciparum, artemisinin-based combination therapy (ACT) is currently treatment of choice for malaria in the vast majority...

journal_title：Malaria journal

authors： Adam I,Ibrahim Y,Gasim GI

更新日期：2018-03-13 00:00:00

abstract：BACKGROUND:Private sector availability and use of malaria rapid diagnostic tests (RDTs) lags behind the public sector in Kenya. Increasing channels through which quality malaria diagnostic services are available can improve access to testing and help meet the target of universal diagnostic testing. Registered pharmacie...

journal_title：Malaria journal

authors： Poyer S,Musuva A,Njoki N,Okara R,Cutherell A,Sievers D,Lussiana C,Memusi D,Kiptui R,Ejersa W,Dolan S,Charman N

更新日期：2018-03-13 00:00:00

abstract：BACKGROUND:Artemisinin-based combination therapy is the first-line anti-malarial treatment for uncomplicated Plasmodium falciparum infection in Angola. To date, the prevalence of polymorphisms in the pfk13 gene, associated with artemisinin resistance, and pfmdr1, associated with lumefantrine resistance, have not been s...

journal_title：Malaria journal

authors： Ljolje D,Dimbu PR,Kelley J,Goldman I,Nace D,Macaia A,Halsey ES,Ringwald P,Fortes F,Udhayakumar V,Talundzic E,Lucchi NW,Plucinski MM

更新日期：2018-02-20 00:00:00

abstract：BACKGROUND:Malaria caused by Plasmodium ovale spp. has been neglected by and large from research and has received only little scientific attention during the past decades. Ovale malaria is considered to feature relapses by liver hypnozoites although scientific evidence for this paradigm is scarce. CASE PRESENTATION:He...

journal_title：Malaria journal

authors： Veletzky L,Groger M,Lagler H,Walochnik J,Auer H,Fuehrer HP,Ramharter M

更新日期：2018-02-09 00:00:00

abstract：BACKGROUND:There is evidence that suggests that undernutrition has a detrimental effect on malarial immunity in children. The aim of the study was to discover whether nutrient supplementation improved development of malarial antibody immunity in children up to 18 months of age. METHODS:The study was conducted with a s...

journal_title：Malaria journal

authors： Barua P,Chandrasiri UP,Beeson JG,Dewey KG,Maleta K,Ashorn P,Rogerson SJ

更新日期：2018-02-07 00:00:00

abstract：BACKGROUND:Eradication of malaria is difficult because of the ability of hypnozoite, the dormant liver-stage form of Plasmodium vivax, to cause relapse in patients. Research efforts to better understand the biology of P. vivax hypnozoite and design relapse prevention strategies have been hampered by the lack of a robus...

journal_title：Malaria journal

authors： Pewkliang Y,Rungin S,Lerdpanyangam K,Duangmanee A,Kanjanasirirat P,Suthivanich P,Sa-Ngiamsuntorn K,Borwornpinyo S,Sattabongkot J,Patrapuvich R,Hongeng S

更新日期：2018-01-25 00:00:00

abstract：:The Rethinking Malaria Leadership Forum, held at Harvard Business School in February 2017 with collaboration of the Barcelona Institute for Global Health and the Swiss Tropical and Public Health Institute, identified this training gap as a high priority for both analysis and action. The gap in human resource training ...

journal_title：Malaria journal

authors： Wirth DF,Casamitjana N,Tanner M,Reich MR

更新日期：2018-01-25 00:00:00

abstract：BACKGROUND:The Democratic Republic of the Congo (DRC) bears a high burden of malaria, which is exacerbated in pregnant women. The VAR2CSA protein plays a crucial role in pregnancy-associated malaria (PAM), and hence quantifying diversity at the var2csa locus in the DRC is important in understanding the basic epidemiolo...

journal_title：Malaria journal

authors： Verity R,Hathaway NJ,Waltmann A,Doctor SM,Watson OJ,Patel JC,Mwandagalirwa K,Tshefu AK,Bailey JA,Ghani AC,Juliano JJ,Meshnick SR

更新日期：2018-01-24 00:00:00

abstract：:The hypnozoite reservoir of Plasmodium vivax represents both the greatest obstacle and opportunity for ultimately eradicating this species. It is silent and cannot be diagnosed until it awakens and provokes a clinical attack with attendant morbidity, risk of mortality, and opportunities for onward transmission. The on...

journal_title：Malaria journal

authors： Baird JK,Battle KE,Howes RE

更新日期：2018-01-22 00:00:00

abstract：BACKGROUND:Kohat district is one of the medium intensity malaria transmission areas in Pakistan where asymptomatic carriers are likely to form a reservoir of infection. This study was done to explore the possibility of using microscopy, rapid diagnostic testing (RDT), real time polymerase chain reaction (RT-PCR) and RT...

journal_title：Malaria journal

authors： Naeem MA,Ahmed S,Khan SA

更新日期：2018-01-22 00:00:00

abstract：BACKGROUND:Malaria is highly prevalent in many parts of India and is mostly caused by the parasite species Plasmodium vivax followed by Plasmodium falciparum. Chloroquine (CQ) is the first-line treatment for blood stage P. vivax parasites, but cases of drug resistance to CQ have been reported from India. One of the sur...

journal_title：Malaria journal

authors： Joy S,Mukhi B,Ghosh SK,Achur RN,Gowda DC,Surolia N

更新日期：2018-01-19 00:00:00

abstract：BACKGROUND:This study was designed to evaluate the efficacy of exchange transfusion in patients with severe imported falciparum malaria. Twelve patients who met the diagnostic criteria for severe malaria were treated with exchange transfusion 14 times according to a conventional anti-malarial treatment. This study eval...

journal_title：Malaria journal

authors： Lin J,Huang X,Qin G,Zhang S,Sun W,Wang Y,Ren K,Xu J,Han X

更新日期：2018-01-16 00:00:00